Does Grace Ashcroft, the main character in Resident Evil Requiem, have a family connection with Alyssa Ashcroft from Resident Evil Outbreak?
The first trailer of Resident Evil Requiem shows a dialogue mentioning that Grace's mother, named Alyssa, passed away eight years ago.

The Connection with Alyssa Ashcroft from Biohazard: Outbreak
The name Alyssa Ashcroft might sound familiar to fans of the old series, as she is an NPC character in the spin-off game Biohazard: Outbreak. Alyssa is a journalist who appears in that game, and now there is a possibility that Grace is Alyssa's daughter. Fans speculate that Requiem will connect the classic story with the new one.
Other supporting evidence: in Resident Evil 7, there is a newspaper article written by Alyssa Ashcroft.
Resident Evil Requiem is not just a new title in the franchise, but also serves as a narrative bridge between past and present. The presence of Grace Ashcroft as the protagonist daughter of Alyssa Ashcroft could be a key element in the plot and bring greater emotional depth. While waiting for gameplay and other official stories, this theory is increasingly attracting fans' attention.